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Farnesyl S-Thiolodiphosphate (FSPP)


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Catalog No.:  I-S150
MW: 449.48
CAS: 373597-45-6

Description:  Farnesyl thiolodiphosphate (FSPP) is an analog of FPP in which the non-bridging oxygen has been replaced by sulfur resulting in a less-reactive compound.

Provided as the tris-ammonium salt

Storage

-20°C or below

Featured In Publications:

1) Phan, R. M. and C. D. Poulter (2001). "Synthesis of (S)-Isoprenoid Thiodiphosphates as Substrates and Inhibitors." The Journal of Organic Chemistry 66(20): 6705.
2) Hast, M. A., C. B. Nichols, et al. (2011). "Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens." Journal of Biological Chemistry 286(40): 35149-35162.
3) Lee, L. V., B. Granda, et al. (2010). "Biophysical Investigation of the Mode of Inhibition of Tetramic Acids, the Allosteric Inhibitors of Undecaprenyl Pyrophosphate Synthase." Biochemistry 49(25): 5366.

Bulk discounts available, please email echelon@echelon-inc.com for information.


Options/Sizes Pricing
I-S150-1mg $ 258.00
I-S150-10mg $ 1,612.00
Additional Information:
Tech Data Sheet - I-S150


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