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Sphingosine 1-phosphate fluorescein (S1P Fluorescein)


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Catalog No.:  S-200F
MW: 769.8

Description:  Echelon offers a unique selection of sphingosine 1-phosphate analogs labeled at the terminus of the alkyl chain with biotin or fluorescent groups. All compounds have the natural erythro stereochemistry and are synthesized from chiral precursors.

Storage

S1P fluorescein is relatively stable at room temperature as a solid. It is best stored as a dried solid, protected from light at -20ºC. Solutions/emulsions should be kept at -20ºC. Storage in basic buffers (pH > 9.0) or acidic buffers (pH < 4.0) may cause decomposition.

Excitation/Emission

494/521 nm

Solubility

MeOH >1 mg/ml

Featured in Publications

1) Peest, U., S. C. Sensken, et al. (2008). "S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake." J Cell Biochem 104(3): 756-72.
2) Meissner, A., J. Yang, et al. (2012). "Tumor Necrosis Factor-α-Mediated Downregulation of the Cystic Fibrosis Transmembrane Conductance Regulator Drives Pathological Sphingosine-1-Phosphate Signaling in a Mouse Model of Heart Failure." Circulation 125(22): 2739-2750.

Bulk quantities of this product are available. Please email echelon@echelon-inc.com for more information.


Options/Sizes Pricing
S-200F-1ea $ 347.00
Additional Information:
Tech Data Sheet - S-200F


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