Sphingosine Kinase Inhibitor (SKI-II)

		Catalog No.:  B-0024 MW: 339.2 Purity: 97% CAS: 312636-16-1 Description:  2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole (SK1-II) is a cell permeable, potent, and specific inhibitor of sphingosine kinase (IC50 = 0.5 μM). The compound does not bind to the ATP-binding site and does not affect the kinase activities of hERK2, hPI3K, or hPKCα at concentrations up to 60 μM. SK1-II showed anti-tumor properties, inducing apoptosis in a number of cell lines including those that express Pgp or MRP1 drug-transport proteins.
Solubility DMSO
Options/Sizes Pricing B-0024-10mg $ 66.00 B-0024-50mg $ 307.00
Additional Information: Tech Data Sheet - B-0024
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