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Phosphatidylinositol 4-phosphate diC4 (PI(4)P diC4)


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Catalog No.:  P-4004
MW: 620.32
CAS: 790192-01-7

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.

Storage

-20°C

Featured in Publications:

1) Guo, J., M. R. Wenk, et al. (2003). "Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles." Proc Natl Acad Sci U S A 100(7): 3995-4000.
2) Schoebel, S., W. Blankenfeldt, et al. (2010). "High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA." EMBO Rep 11(8): 598.
3) Ramel, D., F. Lagarrigue, et al. (2011). "Shigella flexneri Infection Generates the Lipid PI5P to Alter Endocytosis and Prevent Termination of EGFR Signaling." Sci. Signal. 4(191): ra61-

Product Keywords: Dibutanoyl Phosphatidylinositol 4-phosphate, PtdIns(4)P, PI(4)P, or PI4P

Bulk discounts available, please email echelon@echelon-inc.com for information.


Options/Sizes Pricing
P-4004-100ug $ 94.00
P-4004-500ug $ 286.00
P-4004-1mg $ 494.00
Additional Information:
PIP FAQs - PIP FAQ's

Tech Data Sheet - P-4004 Sodium Salt


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assay and reagents for drug discovery in lipid signaling pathways