Glycerophosphoinositol 4,5-diphosphate (GroPI(4,5)P2)

Catalog No.:  P-4500
MW: 604.1
CAS: 111188-72-8

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).


-20 °C

Featured in Publication:

1) Zizza, P., C. Iurisci, et al. (2012). "Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity." J Biol Chem 287(20): 16849-16859.

Product Keywords: Glycerophosphatidylinositol 4,5-bisphosphate, GroPtdIns(4,5)P2, GroPI(4,5)P2, or GroPI45P2

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Options/Sizes Pricing
P-4500-100ug $ 102.00
P-4500-500ug $ 313.00
P-4500-1mg $ 540.00
Additional Information:

Tech Data Sheet - P-4500

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assay and reagents for drug discovery in lipid signaling pathways