PI(3,4,5)P3 Phosphatase (SHIP2) Activity Assay Service

Catalog No.:  T-1400

Description:  The PI(3,4,5)P3 Phosphatase (SHIP2) Activity Assay Service uses the 5’ PtdIns(3,4,5)P3 Phosphatase Activity Fluorescence Polarization Assay (K-1400) kit. This service has been designed to quantify the activity of immunoprecipitated 5' phosphatases and/or to screen SHIP2 (E-1000) inhibitors.

The PI(3,4,5)P3 Phosphatase (SHIP2) Activity Assay Service is a competitive assay for the product of the phosphatase reaction PI(3,4)P2. After the Phosphatase reactions are complete, reaction products are mixed with a PI(3,4)P2 detector protein and the fluorescent PI(3,4)P2 probe. Polarization (mP) values decrease as probe binding to the PI(3,4)P2 detector is displaced by PI(3,4)P2 produced from enzymatic activity.

Please refer to the technical data sheet for sample considerations and shipping information.  To place an order please contact Echelon at 801.588.0455.

Options/Sizes Pricing
T-1400-10ea $ 618.00
T-1400-20ea $ 1,030.00
T-1400-30ea $ 1,391.00
T-1400-40ea $ 1,648.00

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assay and reagents for drug discovery in lipid signaling pathways