ZSTK474 (PI3K Inhibitor)

Catalog No.:  B-0307
MW: 417.41
Purity: 99%
CAS: 475110-96-4

Description:  ZSTK474 is a potent inhibitor of all four isoforms of class I PI 3-kinase (α 6.7 nM, β 10.4 nM, γ 11.7 nM, δ 1.8 nM). It binds to the ATP-binding pocket and is more active and less toxic than LY294002. ZSTK474 shows anti-tumor activity against human xenografts (A549, PC-3, WiDr) in mice by arresting cell growth. In addition, it was able to inhibit osteoclast formation and collagen-induced arthritis in a mouse model.



Options/Sizes Pricing
B-0307-5mg $ 78.00
B-0307-25mg $ 140.00
B-0307-100mg $ 234.00
Additional Information:
Tech Data Sheet - TDS_B-0307_ rev1

Add a specific quantity to your cart    *  

Back to the webstore startpage      Back to the product overview      Your Shopping Cart      Terms of Service

assay and reagents for drug discovery in lipid signaling pathways