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N-Stearoyl Ceramide 1-phosphate


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Catalog No.:  S-5018
MW: 662.96
CAS: 202063-34-1 (free acid)

Description:  Ceramide 1-phosphate (C1P) is biosynthesized from ceramide by the intracellular enzyme Ceramide kinase. C1P inhibits cell apoptosis via inhibition of acid sphingomyelinase activity in contrast to ceramide which promotes apoptosis. C1P is important in inflammation, activating cytosolic phospholipase A2 alpha and releasing downstream inflammatory mediators. In addition, C1P is involved in DNA synthesis, mast cell degranulation and neutrophil phagocytosis.

Storage:

-20°C or below

Solubility:

CHCl3:MeOH:H2O (10:15:1) >1 mg/mL

Related Products:

Ceramide Kinase Inhibitor Screen (K-4600)
NVP231 (Ceramide Kinase Inhibitor) (B-0040)
Ceramide Kinase, active (E-K084F)


Options/Sizes Pricing
S-5018-1mg $ 77.00
S-5018-5mg $ 298.00
S-5018-10mg $ 485.00

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assay and reagents for drug discovery in lipid signaling pathways