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D-myo-Phosphatidylinositol 3,4,5-trisphosphate 17:0/16:0


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Catalog No.:  P-3917
MW: 1152.93

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2

Storage

-20° C

Product Keywords: Dipalmitoyl Phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3, PI(3,4,5)P3, or PIP3

Bulk discounts available, please email echelon@echelon-inc.com for information.


Options/Sizes Pricing
P-3917-100ug $ 48.00
P-3917-500ug $ 223.00
P-3917-1mg $ 398.00
Additional Information:
Tech Data Sheet - TDS_P-3917_Rev1


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assay and reagents for drug discovery in lipid signaling pathways