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Collagen Hybridizing Peptide - Biotin conjugate (CHP)


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Catalog No.:  C-660B
MW: 2762
Purity: 95%

Collagen Hybridizing Peptide (CHP) is labeled with either carboxyfluorescein (Cat#: C-660F) for fluoroscence detection or biotin (Cat#: C-660B) for avidin/streptavidin-mediated detection. When used on minimally processed tissue samples (e.g., cryosections), it can visualize the presence of denatured collagen in pathological tissues [2]. It can also be used in place of failed collagen antibodies to detect collagen on highly processed tissue samples [3]. In addition, CHP allows direct and specific detection of collagen bands in SDS-PAGE gels without the need of western blot [3].

Storage

-20 °C

References

1) Li, Y and Yu SM “Targeting and mimicking collagens via triple helical peptide assemblies” Curr Opin Chem Biol, 2013, 17, 968-975.
2) Li Y, Foss CA, Summerfield DD, Doyle JJ, Torok CM, Dietz HC, Pomper MG, and Yu SM “Targeting collagen strand by photo-triggered triple-helix hybridization” Proceedings of the National Academy of Sciences of the United States of America, 2012, 109, 14767-14772. DOI: 10.1073/pnas.1209721109.
3) Li Y, Ho D, Huan M, Chan TR, An B, Yu H, Brodsky B, Jun AS, and Yu SM “Direct detection of collagenous proteins by fluorescently labeled collagen mimetic peptides” Bioconjugate Chemistry, 2013, 24, 9-16. DOI: 10.1021/bc3005842.

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Options/Sizes Pricing
C-660B-300ug $ 550.00
Additional Information:
Tech Data Sheet - TDS_C-600B_rev2


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