Collagen IV ELISA Kit II
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Catalog No.: K-1700s Description: The Collagen IV ELISA Kit II is a sandwich ELISA for the quantification of soluble human Collagen IV. Assay Range: 3.1-200 ng/mL Collagen IV Sample Volume: 20 μL/sample for results in duplicate |
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Product background: Collagen IV is a major component of the extracellular matrix and provides the main structural support for the basement membrane. It has been demonstrated that a variety of diseases cause alterations in Collagen IV synthesis, degradation and release at the tissue level. The serum level of Collagen IV is altered in several types of diseases, including liver fibrosis (a good index with hyaluronic acid) and cirhosis. Research has shown that the loss of Collagen IV in the basement membrane (with a concurrent increase in collagenase activity) positively correlates with the progression of cancer. Collagen IV in the sera may be indicative of tissue Collagen IV degradation and may correlate with cancer progression. |
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Additional Information:
Tech Data Sheet - TDS_K-1700s_Rev 1 |
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