Collagen IV ELISA Kit II

Product background: Collagen IV is a major component of the extracellular matrix and provides the main structural support for the basement membrane. It has been demonstrated that a variety of diseases cause alterations in Collagen IV synthesis, degradation and release at the tissue level. The serum level of Collagen IV is altered in several types of diseases, including liver fibrosis (a good index with hyaluronic acid) and cirhosis. Research has shown that the loss of Collagen IV in the basement membrane (with a concurrent increase in collagenase activity) positively correlates with the progression of cancer. Collagen IV in the sera may be indicative of tissue Collagen IV degradation and may correlate with cancer progression.

Echelon's Collagen IV ELISA Kit II is a quantitative sandwich immunoassy designed for in vitro measurement of collagen IV levels in biological samples. The concentration of collagen IV with the sample is determined using a standard curve of known amounts of collagen IV.

Related Products:
Hyaluronan Enzyme-Linked Immunosorbent Assay (K-1200)
Hyaluronic Acid Sandwich ELISA (K-4800)
Collagen IV Assay Service (T-1700)

Keywords: Hyaluronan, Liver fibrosis, COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6