Products

Lysophosphatidic Acid (LPA) Antibody (504B3)


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Catalog No.:  Z-P200

Description:  Purified Anti-Lysophosphatidic Acid (LPA) monoclonal antibody.
Subclass: IgGk1
Source: Mouse
Applications: ELISA, Immunohistochemistry, Immunocytochemistry

Product Background: Lysophosphatidic Acid (LPA) is a serum-derived phospholipid involved in diverse ceullular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogensis, tumor invasion, and smooth muscle contraction. Recent research indicates LPA may play a significant role in the pathophysiology of cancer and may be used as a biomarker for ovarian cancer. LPA Antibody (504B3) was originally developed and patented at Lpath Therapeutics.

Storage

Antibody is stable for up to 1 year at -20 °C. Antibody is stable for 60 days at 4°C. Avoid repeated freeze/thaw cycles.

References

1) J. Cheng, S. Sahani, T.J. Hausrat, et al. (2016) "Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling" Neuron, 92(1); 126-142. doi: doi:10.1016/j.neuron.2016.08.035
2) M. Balood, H. Zahednasab, et al. (2014) "Elevated serum levels of lysophosphatidic acid in patients with multiple sclerosis" Hum. Immunol. 75(5); 411-413, doi: 10.1016/j.humimm.2014.02.021
3) Y. Goldshmit, R. Matteo, et al. (2012) "Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes." Am. J. Pathol. , 181(3): 978-992, doi: 10.1016/j.ajpath.2012.06.007

Bulk discounts available, please email echelon@echelon-inc.com for information.


Options/Sizes Pricing
Z-P200-10ug $ 75.00
Z-P200-50ug $ 250.00
Z-P200-250ug $ 1,000.00
Additional Information:
Tech Data Sheet - TDS_Z-P200_Rev3


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