Products

Purified Anti-PtdIns(3,4)P2 IgG

 
Catalog No.:  Z-P034

Description:  Purified Anti-PtdIns(3,4)P2 antibody
Subtype: IgG3
Source: Mouse
Applications: ELISA, Immunofluorescence, Protein-Lipid Overlay

Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.

Storage

2-8 °C for up to 30 days, -20 °C for greater than 30 days. Do not freeze thaw multiple times.

Featured in Publications

1) Chiang, H. C., L. Wang, et al. (2010). "PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila." Proc Natl Acad Sci U S A 107(15): 7060-5.

Related Products

Biotinylated Anti-PtdIns(3,4)P2 IgG (Z-B034)
Phosphatidylinositol 3,4-bisphosphate, diC8 (P-3408)
Phosphatidylinositol 3,4-bisphosphate, diC16 (P-3416)


Options/Sizes Pricing
Z-P034-10ug $ 134.00
Z-P034-50ug $ 370.00
Z-P034-250ug $ 1,296.00
Additional Information:
Tech Data Sheet - Z-P034

Protocol - Protocol for immunofluorescence in chamber slides

Protocol b - Protocol for frozen tissue sections


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assay and reagents for drug discovery in lipid signaling pathways