Products

PI(3,4)P2 PIP Beads™


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Catalog No.:  P-B034a

Description:  PI(3,4)P2 PIP BeadsTM are composed of agarose with 10 nanomoles of bound PI(3,4)P2 per mL of beads, enough for several protein binding experiment. Each 1 mL order of PIP Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.

Storage

  • 4 °C - do not freeze

Applications

  • PIP BeadsTM are designed for use in protein pull-down experiments to identify and characterize phosphoinositide binding proteins. Possible applications include the isolation of PIP-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis.

Featured in Publication

1) Wullschleger, S., D. H. Wasserman, et al. (2011). "Role of TAPP1 and TAPP2 adaptor binding to PtdIns(3,4)P2 in regulating insulin sensitivity defined by knock-in analysis." Biochemical Journal 434(2): 265-274.

Being bio-reactive blog: "Lipid-Ligand interaction tools: lipids are not scary intermediates anymore"


Options/Sizes Pricing
P-B034a-0.1ml $ 99.00
P-B034a-1ml $ 515.00
Additional Information:
Tech Data Sheet - TDS_P-Bxxx_ Rev 7

Protocol - Protocol


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assay and reagents for drug discovery in lipid signaling pathways