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Phosphatidylinositol diC4 (PI diC4)


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Catalog No.:  P-0004

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Storage

-20 °C

Featured in Publications:

1) ,Guo, J., M. R. Wenk, et al. (2003). "Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles." Proc Natl Acad Sci U S A 100(7): 3995-4000.
2) He, F., M. Mao, et al. (2004). "Enhancement of phototransduction g protein-effector interactions by phosphoinositides." J Biol Chem 279(10): 8986-90.
3) Kobayashi, M., R. K. Mutharasan, et al. (2004). "Identification of hydrophobic interactions between proteins and lipids: free fatty acids activate phospholipase C delta1 via allosterism." Biochemistry 43(23): 7522-33.

Product Keywords: Dibutanoyl Phosphatidylinositol, PtdIns, or PI,

Bulk discounts available, please email echelon@echelon-inc.com for information.


Options/Sizes Pricing
P-0004-100ug $ 66.00
P-0004-500ug $ 232.00
P-0004-1mg $ 414.00
Additional Information:
Tech Data Sheet - P-0004


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assay and reagents for drug discovery in lipid signaling pathways