Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8)

Catalog No.:  P-5008
MW: 732.53
CAS: 214068-76-5

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases.


-20 °C

Featured in Publications:

1) Ikonomov, O. C., D. Sbrissa, et al. (2002). "Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity." J Biol Chem 277(11): 9206-11.
2) Hinchliffe, K. A., M. L. Giudici, et al. (2002). "Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms." Biochem J 363(Pt 3): 563-70.
3) Sbrissa, D., O. C. Ikonomov, et al. (2002). "Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells." J Biol Chem 277(49): 47276-84.

Product Keywords: Dioctanoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P, PI(5)P, or PI5P

Bulk discounts available, please email for information.

Options/Sizes Pricing
P-5008-100ug $ 44.00
P-5008-500ug $ 193.00
P-5008-1mg $ 359.00
Additional Information:
Tech Data Sheet - P-5008 Sodium Salt


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assay and reagents for drug discovery in lipid signaling pathways