Glycerophosphoinositol (GroPI)

Catalog No.:  P-0000
MW: 356.2
CAS: 129830-95-1

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.


-20 °C

Featured in Publication:

1) Zizza, P., C. Iurisci, et al. (2012). "Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity." J Biol Chem 287(20): 16849-16859.
2) Vessichelli, M., et al. (2017). "The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses." Journal of Biological Chemistry 292(31): 12828-12841.

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Product Keywords: Dioctanoyl Phosphatidylinositol, PtdIns, or PI,

Bulk discounts available, please email for information.

Options/Sizes Pricing
P-0000-100ug $ 117.00
P-0000-500ug $ 355.00
P-0000-1mg $ 612.00
Additional Information:

Tech Data Sheet - P-0000

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assay and reagents for drug discovery in lipid signaling pathways