S32826 [4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt]

Catalog No.:  L-3282
MW: 441.2
Purity: 98%
CAS: 1103672-43-0

Description:  S32826 is a potent inhibitor of the enzyme autotaxin, with an IC50 in the nanomolar range. S32826 is suitable for in vitro studies using purified components or cultured cells. Due to its short circulation half-life, S32826 is not recommended for use in animal models.


-20 °C

Featured in Publications:

1) Ferry, G., N. Moulharat, et al. (2008). "S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool." J Pharmacol Exp Ther 327(3): 809-19.
2) Conrotto, P., U. Andrasson, et al. (2011). "Knock-down of SOX11 induces autotaxin-dependent increase in proliferation in vitro and more aggressive tumors in vivo." Molecular Oncology 5(6): 527.
3) Li, S., C. Xiong, et al. (2012). "ATX and LPA receptor 3 are coordinately up-regulated in lipopolysaccharide-stimulated THP-1 cells through PKR and SPK1-mediated pathways." FEBS Letters 586(6): 792.

Related Products:

Autotaxin Inhibitors: BrP-LPA (L-7416), HA130 (B-0701)
Autotaxin, active (E-4000)
FS-3, Fluorogenic ATX Substrate (L-2000)
ATX-Red AR-2, ATX Imaging Agent (L-2010)
Autotaxin Activity Assay (
K-4100) & Inhibitor Screening Kits (K-4200 and K-4200HTS)

Options/Sizes Pricing
L-3282-1mg $ 60.00
L-3282-5mg $ 147.00
Additional Information:
Tech Data Sheet - L-3282

Add a specific quantity to your cart    *  

Back to the webstore startpage      Back to the product overview      Your Shopping Cart      Terms of Service

assay and reagents for drug discovery in lipid signaling pathways