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Purified Mouse Anti-LBPA (BMP)


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Catalog No.:  Z-PLBPA

Description:  Purified anti-LBPA monoclonal antibody
Subclass: IgG1k (clone 6C4)
Source: Mouse
Applications: Immunofluorescence, ELISA

This antibody recognizes an important but unusual eukaryotic lipid, lysobisphosphatidic acid, (LBPA) also termed bis(monoacylglyceryl)phosphate (BMP). LBPA is found primarily in late endosomes and is a cellular marker of this compartment. Further, LBPA is a lipid antigen for the autoimmune disorder, anti-phospholipid syndrome (APS).

Storage

Store at -20 °C for up to 60 days. A preservative such as sodium azide (final concentration, 0.02%) can be added if it wil not interfere with specific applications, i.e. peroxidase activity. Aliquot and store at -20 or -70 °C if longer storage is necessary. Avoid repeated freeze/thaw cycles.

Featured in Publications

1) Kobayashi, T., M. H. Beuchat, et al. (1999). "Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport." Nat Cell Biol 1(2): 113-8.
2) Zornetta, I., L. Brandi, et al. (2010). "Imaging the cell entry of the anthrax oedema and lethal toxins with fluorescent protein chimeras." Cell Microbiol 12(10): 1435-45.
3) Otomo, T., K. Higaki, et al. (2011). "Lysosomal Storage Causes Cellular Dysfunction in Mucolipidosis II Skin Fibroblasts." J Biol Chem 286(40): 35283-90.

Related Products

Anti-LBPA Antibody (6C4) in cell supernatant (Z-SLBPA)
(S,S) Bisoleoyl-lyso bisphosphatidic acid (L-B181)
Biotin-(R,R)-2,2’-Bisdodecyl-LBPA (biotin-C12-ether LBPA) (L-B1B12)
Anti-Lysobisphosphatidic Acid (LBPA) Human IgG ELISA (K-4900)


Options/Sizes Pricing
Z-PLBPA-10ug $ 142.00
Z-PLBPA-50ug $ 381.00
Additional Information:
Tech Data Sheet - TDS_Z-PLBPA_Rev 2x


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