Phosphatidylinositol 3,4,5-trisphosphate 18:0/20:4

Catalog No.:  P-3924
MW: 1214.99

Description:  Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.


-20 °C

Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3, PI(3,4,5)P3, or PIP3

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Options/Sizes Pricing
P-3924-100ug $ 127.00
P-3924-500ug $ 562.00
P-3924-1mg $ 955.00
Additional Information:
Tech Data Sheet - TDS_P-3924_Rev1

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assay and reagents for drug discovery in lipid signaling pathways