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1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 LPG)


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Catalog No.:  L-5216
MW: 506.26
CAS: 326495-22-1

Description:  Lysophospholipids are lipid mediators which elicit a diverse array of cellular responses through activation of phospholipid specific G protein-coupled receptors. Lysophosphatidylglycerol (LPG) increases intracellular Ca2+ release and induces phosphorylation on ERK and Akt in OVCAR3 cells however the exact receptor has not been identified. LPG can also modulate the formyl peptide like-1 activated inflammatory response in human phagocytes.

Storage

-20 °C or below

References

1). K. Makide, et al “Novel lysophosphoplipid receptors: their structure and function” Journal of Lipid Research, 2014, 55, 1986;
2) J.W. Shim, et al. “Lysophosphatidylglycerol inhibits formyl peptide receptor like-1-stimulated chemotactic migration and IL-1? production from human phagocytes” Exp. Mol. Med., 2009, 41, 584-591.
3) K.S Park, et al. “Effect of lysophosphatidylglycerol on several signaling molecules in OVCAR-3 human ovarian cancer cells: involvement of pertussis toxin-sensitive G-protein coupled receptor.” Biochem. Pharmacol., 2007, 73, 675-81.


Options/Sizes Pricing
L-5216-10mg $ 50.00
Additional Information:
Tech Data Sheet - TDS_L-5216_Rev 1


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assay and reagents for drug discovery in lipid signaling pathways