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9(10)-Nitrooeleic Acid


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Catalog No.:  L-0112
MW: 327.24

Nitrooleic acid (OA-NO2) is formed by nitration of oleic acid from excessive nitric oxide during inflammation (nitrative stress). OA-NO2 is a potent signaling molecule which can activate numerous receptors including TRPA1 cation channels and PPARγ. 9(10)-Nitrooleic acid is a mixture of the 9-nitro and 10-nitro isomers which are formed in equal amounts in vivo.

Storage

-20 °C or below

References

1. P.S. Baker et al “Fatty Acid Transduction of Nitric Oxide signaling” Journal of Biological Chemistry, 2005, 280, 42464-42475;
2. F.J. Schopfer et al “Covalent Peroxisome Proliferator-Activated Receptor Adduction By Nitro-Fatty Acid” Journal of Biological Chemistry, 2010, 285, 12321-12333.


Options/Sizes Pricing
L-0112-500ug $ 85.00
L-0112-1mg $ 159.00
Additional Information:
Tech Data Sheet - TDS_L-0112_Rev 1


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assay and reagents for drug discovery in lipid signaling pathways