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Scientific Background - Liver Disease

Serum Hyaluronic Acid levels have been shown to correlate with liver fibrosis and cirrhosis states. Multiple studies have shown that serum HA levels are directly corelated to liver disease Echelons Hyaluronic Acid ELISA measures HA levels in all biological fluids. World J Gastroenterol. 2005 Jan 28; 11(4):476-6-81.Noninvasive estimation of liver fibrosis and response to interferon therapy by a serum fibrogenesis marker, YKL-40, in patients with HCV-associated liver disease. Nakano T. et al.

Guechot J, et al. Diagnostic accuracy of hyaluronan and PIIIP serum assays as markers of liver fibrosis in chronic viral hepatitis C evaluated by ROC curve analysis. Clin Chem1996;42:558

assay and reagents for drug discovery in lipid signaling pathways