AS1949490 (SHIP2 Inhibitor)

Name: AS1949490 (SHIP2 Inhibitor)
SKU: B-0342
Price: 97 USD
Availability: InStock

AS1949490 is a potent, selective SHIP2 inhibitor with IC50 of 0. [Read More...]

AS1949490 is a potent, selective SHIP2 inhibitor with IC50 of 0.62 uM for human, which shows less effect on SHIP1 or no effects on some other types of intracellular phosphatases (such as PTEN, synaptojanin, and myotubularin). This compound also activates intracellular insulin signaling pathways in the liver and displays gluconeogensis regulation and antidiabetic effects.

References

A. Suwa, T. Yamanoto, et al. “Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2”, British Journal of Pharmacology, 2009,158, 879-88.

Categories	Biochemical Reagents
Filter	Inhibitor, SHIP
CAS Number	1203680-76-5
Molecular Formula	C20H18ClNO2S
Molecular Weight (g/mol)	371.88
Purity	>95%
Storage	4 °C or below
Shipping Temp	Ambient Temperature