Dimethylallyl thiolodiphosphate (DMASPP) is an analog of DMAPP in which the non-bridging oxygen has been replaced by sulfur resulting in a less-reactive compound.
Provided as the tris-ammonium salt
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Publications
Powered by Bioz1. Phan, R. M. and C. D. Poulter (2001). “Synthesis of (S)-Isoprenoid Thiodiphosphates as Substrates and Inhibitors.” The Journal of Organic Chemistry 66(20): 6705.
2. Hosfield, D. J., Y. Zhang, et al. (2004). “Structural Basis for Bisphosphonate-mediated Inhibition of Isoprenoid Biosynthesis.” Journal of Biological Chemistry 279(10): 8526-8529.
3. Köksal, M., et al. (2010). “Structure of Isoprene Synthase Illuminates the Chemical Mechanism of Teragram Atmospheric Carbon Emission.” Journal of Molecular Biology 402(2): 363-373.
4. Miyamoto, K., et al. (2014). “A 7-dimethylallyl tryptophan synthase from a fungal Neosartorya sp.: Biochemical characterization and structural insight into the regioselective prenylation.” Bioorganic & Medicinal Chemistry 22(8): 2517-2528.
5. Elshahawi, S. I., et al. (2017). “Structure and specificity of a permissive bacterial C-prenyltransferase.” Nat Chem Biol 13: 366.
