Bisepoxy Juvenile Hormone III (mixture of diastereomers) is a sesquiterpenoid biosynthesized via the mevalonate pathway in the ring-glands of higher dipterans.
Juvenile Hormones are sesquiterpenoids found in insects that regulates important physiological processes such as reproduction and metamorphosis. Bisepoxy juvenile hormone III (JHB3) is biosynthesized via the mevalonate pathway in the ring-glands of higher dipterans (flies).
References
1) J.A. Tillman, S.J. Seybold, R.A Jurenka, R.A., et al. “Insect pheromones – an overview of biosynthesis and endocrine regulation.” Insect Biochemistry and Molecular Biology, 1999, 29(6), 481-514.
2) D.S. Richard, S.W. Applebaum, et al “Juvenile hormone bisepoxide biosynthesis in vitro by the ring gland of Drosophila melanogaster: a putative juvenile hormone in the higher Diptera” Proc. Nat. Sci Acad., 1989, 86 (4), 1421-1425.
3) K.S. Lefevere, K.S. Lacey, et al. “Identification and quantification of juvenile hormone biosynthesized by larval and adult Australian sheep blowfly Lucilia cuprina (Diptera: Calliphoridae).” Insect Biochem Mol. Bio., 1993, 23(6), 713-20.
Keywords: trans-7,8,10,11-Bisepoxyfarnesenic Acid methyl ester
