Recombinant anti-Annexin V Nanobody, Clone # Nb36, COOH-terminal HA tag.
Type: VHH single domain
Source: E. Coli
Applications: ELISA, Immunoprecipitation, Pull down
Clonality: Monoclonal
Background: Annexin V VHH Antibody was produced in a llama with a recombinant full length Annexin V then cloned for recombinant production in E. Coli. Annexin V, aka Annexin A5, is a 36 kDa protein that binds to the negatively charged phospholipid phosphatidylserine, a marker of apoptosis when it is exposed on the plasma membrane outer leaflet. Annexin V is often used as an indicator of apoptosis in flow cytometry experiments and anti-annexin A5 antibodies are commonly found in antiphospholipid syndrome patients.
Recombinant anti-Annexin V Nanobody 36 was developed by Gulliver Biomed.
Storage
Store at -20°C upon arrival. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.
Publications
1) Steels, A. et al. (2018). Intracellular displacement of p53 using transactivation domain (p53 TAD) specific nanobodies. mAbs; 10(7): 1045–1059.
Keywords: Annexin V, Annexin A5, nanobody, VHH, antibody, single domain
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