Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3. This analog of PI(4,5)P2 is labeled with the red fluorophore Cyanine 5 (Cy5)
Product Number: C-45C16a
C-45C16a
Cyanine 5 PI(4,5)P2, C16
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. [Read More...]
