Phosphatidylinositol 4,5-bisphosphate 18:0/20:4 is a synthetic, purified PI(4,5)P2.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Among its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).
Product Keywords: Phosphatidylinositol 4,5-bisphosphate, PtdIns(4,5)P2 (18:0/20:4), PI(4,5)P2 (18:0/20:4), or PIP2
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