Sphingomyelin is a lipid constituent in the exoplasmic face of cell membranes. Sphingomyelin is hydrolyzed by Sphingomyelinases to the proapoptotic messenger Ceramide and phosphorylcholine. Biotin Sphingomyelin can be bound to streptavidin coated surfaces for protein binding experiments and assay development.
Featured in Publications:
Back, M. J., et al. (2018). “Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide.” Cell Death & Disease 9(6): 670.
