Purified Anti-PtdIns(4,5)P2 monoclonal antibody conjugated with Tetramethylrhodamine (TMR).
Subclass: IgM
Source: Mouse
Applications: ELISA, Immunofluorescence
Concentration: 0.5 – 1 mg/mL depending on lot number. Please see lot specific TDS.
Product Background: Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3.
