CAS Number: 58-82-2
Molecular Weight: 1060.23
Salt Form: Acetate
Purity: >97%
Sequence (3-letter): Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH
Sequence (1-letter): RPPGFSPFR-OH
Storage: -20 °C or below
Solubility: Soluble up to 1mg/ml in water
Bradykinin is a potent vasodilator peptide that exerts its action through stimulation of specific endothelial receptors. It has been linked with the pathophysiological process that accompanies tissue damage and inflammation. Use of this peptide has been reported for treating human diseases such as hypertension and acute chronic pain disorders.
References
1. Hornig, B. et al. (1997) “Role of Bradykinin in Mediating Vascular Effects of Angiotensin-Converting Enzyme Inhibitors in Humans” Circulation 95 (5): 1115-1118
2. Dray, A. and Perkins, M. (1993) “Bradykinin and inflammatory pain” Trends Neurosci. 16 (3): 99-104
3. Steranka, L.R., et al. (1988) “Bradykinin as a pain mediator: receptors are localized to sensory neurons, and antagonists have analgesic actions” Proc. Natl. Acad. Sci. USA 85 (9): 3245-3249
