CAS Number: 216757-29-8
Molecular Weight: 634.26
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Ac-Ile-Glu-Pro-Asp-pNA
Sequence (1-letter): Ac-IEPD-pNA
Storage: -20 °C or below
Ac-Ile-Glu-Pro-Asp-pNA is a colorimetric substrate for granzyme B. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates several caspases involved in apoptosis.
Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.