NFF-3 (MMP-3 Substrate)

CAS Number: 158584-09-9 Molecular Weight: 1674. [Read More...]

Description
Additional Information

CAS Number: 158584-09-9
Molecular Weight: 1674.83
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(DNP)-NH2
Sequence (1-letter): Mca-RPKPVE(Nva)WR(Lys(DNP))-NH2
Storage: -20 °C or below

MCA-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(DNP)-NH2 (NFF-3) is a FRET-based substrate for MMP-3 (kcat/Km = 218,000 s-1 M-1). There is some cleavage by MMP-9 (kcat/Km = 10,100 s-1 M-1) and not cleaved by MMP-1 & MMP-2.

Activity is quantified by fluorescence (Ex 325 nm, Em 393 nm).