CAS Number: 158584-08-8
Molecular Weight: 1655.75
Salt Form: TFA
Purity: >96%
Sequence (3-letter): MCA-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(DNP)-NH2
Sequence (1-letter): MCA-RPKPYA(Nva)WM(Lys(DNP))-NH2
Storage: -20 °C or below
MCA-Arg-Pro-Lys-Pro-Tyr-Ala-Nva-Trp-Met-Lys(DNP)-NH2 (NFF-2) is a FRET substrate for several matrix metalloproteases. It is hydrolyzed effectively by MMP-2 (kcatKM = 54,000 s-1M-1), MMP-3(kcatKM = 59,400 s-1M-1), & MMP-9 (kcatKM = 53,400 s-1M-1)
Activity is quantified by fluorescence (Ex 325 nm, Em at 393 nm).
