Molecular Weight: 648.35
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Z-Leu-Leu-Leu-AMC
Sequence (1-letter): Z-LLL-AMC
Storage: -20 °C or below
Solubility: DMSO >1 mg/mL
Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome. Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.