CAS Number: 141223-71-4
Molecular Weight: 667.82
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Z-Val-Lys-Met-AMC
Sequence (1-letter): Z-VKM-AMC
Storage: -20 °C or below
Z-Val-Lys-Met-AMC is a fluorogenic substrate for Amyloid A4-Generating Enzyme and the proteasome.
Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.
References
S. Tsubuki, H. Kawasaki, Y. Saito, N. Miyashita, M. Inomata, and S. Kawashima, Biochem. Biophys. Res. Commun., 196, 1195 (1993).
S. Ishiura, T. Nishikawa, T. Tsukahara, T. Momoi, H. Ito, K. Suzuki, and H. Sugita, Neurosci. Lett., 115, 329 (1990).
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