Product Number: S-0302
2,3,22,23-Dioxidosqualene (mixture of diastereomers) is a substrate for oxidosqualene cyclase forming 24,25-oxidolanosterol. [Read More...]
2,3,22,23-Dioxidosqualene (mixture of diastereomers) is a substrate for oxidosqualene cyclase forming 24,25-oxidolanosterol.
| Categories | Biochemical Reagents |
|---|---|
| Filter | Isoprenoid |
| CAS Number | 31063-19-1 |
| Molecular Formula | C30H50O2 |
| Molecular Weight (g/mol) | 442.72 |
| Purity | >95% |
| Storage | -20 °C or below |
| Shipping Temp | Ambient Temperature |
1) Z. Duniec-Dmuchowski, H. L. Fang, S. C. Strom, E. Ellis, M. Runge-Morris and T. A. Kocarek. (2009) “Human pregnane X receptor activation and CYP3A4/CYP2B6 induction by 2,3-oxidosqualene:lanosterol cyclase inhibition” Drug Metab Dispos 37(4), 900-8
2) Lamb, D. C., et al. (2007). “Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis.” Mol Biol Evol 24(8): 1714-1721.
3) Coates, H. W., et al. (2023). “Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase.” eLife 12: e82843.
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