OMPT [L-sn-1-O-oleoyl-2-O-methylglyceryl-3-phosphothionate] is a metabolically-stabilized analog of Lysophosphatidic Acid (LPA) which acts as potent agonist for the LPA3 receptor. Of the two enantiomers, (2S)-OMPT is more potent than (2R)-OMPT showing 5-20 fold more activity in calcium release from LPA3-transfected Sf9 and rat hepatoma Rh7777 cells. (2S)-OMPT is also more potent in inducing calcium release, IL-6 production, and MAPK and Akt phosporylation in OVCAR3 cells.
Product Number: L-9418
L-9418
2S-OMPT
OMPT [L-sn-1-O-oleoyl-2-O-methylglyceryl-3-phosphothionate] is a metabolically-stabilized analog of Lysophosphatidic Acid (LPA) which acts as potent agonist for the LPA3 receptor. [Read More...]
