Benzo[a]pyrene (BaP, 3,4-Benzopyrene, 3,4-Benzpyrene, Benzo[def]chrysene) is a procarcinogenic polyaromatic hydrocarbon (PAH) found in coal tar and other byproducts from the combustion of organic material. It is metabolized by cytochrome P450 1A1 (CYP1A1) to benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide which is carcinogenic. This metabolite intercalates DNA thus disrupting DNA copying and inducing mutations. Benzo[a]pyrene is used as a chemical carcinogen in cancer models.
![Benzo[a]pyrene - Echelon Biosciences](https://www.echelon-inc.com/wp-content/uploads/2019/07/1452.gif "1452.gif")
Product Number: B-0050
B-0050
Benzo[a]pyrene
Benzo[a]pyrene (BaP, 3,4-Benzopyrene, 3,4-Benzpyrene, Benzo[def]chrysene) is a procarcinogenic polyaromatic hydrocarbon (PAH) found in coal tar and other byproducts from the combustion of organic material. [Read More...]
