Recombinant anti-Ezrin Nanobody, Clone # Nb22, COOH-terminal HA tag.
Type: VHH single domain
Source: E. Coli
Applications: ELISA, Immunoprecipitation, Pull down
Clonality: Monoclonal
Background: Ezrin VHH Antibody was produced in a llama with full length human recombinant Ezrin then cloned for recombinant production in E. Coli. Ezrin (aka cytovillin, villin-2) is a member of the ERM protein family (Ezrin, Radixin, Moesin). These act as cross-linkers between membrane proteins and the actin cytoskeleton. Ezrin interacts with NHERF, phospholipids, actin and CD44 and contains a N-terminal FERM domain that anchors the protein to the plasma membrane.
Recombinant anti-human Ezrin nanobody 22 was developed by Gulliver Biomed.
Storage
Store at -20°C upon arrival. For long term storage, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles.
Publications
1) Beghein E, Gettemans J. (2017) Nanobody Technology: A Versatile Toolkit for Microscopic Imaging, Protein-Protein Interaction Analysis, and Protein Function Exploration. Front Immunol; 8:771
Keywords: Ezrin, nanobody, VHH, antibody, cytovillin, villin-2, single domain
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