TT3, together with helper lipid, DMG-PEG2000, Cholesterol, and mRNA formed TT3 lipid nanoparticles (LNPs) which improve the delivery efficiency of firefly luciferase FLuc mRNA over 350-fold in vitro. TT3 LNPs with human factor IX (hFIX) mRNA can efficiently improve the hFIX level to normal physiological values in FIX-knockout mice.
Product No: N-1113
N-1113
TT3
TT3, together with helper lipid, DMG-PEG2000, Cholesterol, and mRNA formed TT3 lipid nanoparticles (LNPs) which improve the delivery efficiency of firefly luciferase FLuc mRNA over 350-fold in vitro. [Read More...]