Urocortin is closely related to corticotropin-releasing factor (CRF) and is widely expressed throughout the nervous system of mammals. Urocortin interacts with the CRF1 and CRF2 receptors and is important in stress-responses and appetite. Urotropin will cause an increase in heart rate and coronary blood flow through binding to CRF2 receptor and can prevent cardiac tissue damage from ischemic injury.
CAS Number: 176591-49-4
Molecular Weight: 4693.52
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
Sequence (1-letter): DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2
Storage: -20 °C or below