CAS Number: 171543-83-2
Molecular Weight: 4704.52
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Asp-Asp-Pro-Pro-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2
Sequence (1-letter): DDPPLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV-NH2
Storage: -20 °C or below
Urocortin is closely related to corticotropin-releasing factor (CRF) and is widely expressed throughout the nervous system of mammals. Urocortin interacts with the CRF1 and CRF2 receptors and is important in stress-responses and appetite. Urotropin will cause an increase in heart rate and coronary blood flow through binding to CRF2 receptor and can prevent cardiac tissue damage from ischemic injury.
