Molecular Weight: 690.36
Salt Form: HCl
Purity: >96%
Sequence (3-letter): Z-Ala-Arg-Arg-4MbNA
Sequence (1-letter): Z-ARR-4MbNA
Storage: -20 °C or below
Z-Ala-Arg-Arg-4MbNA is a fluorogenic substrate for Cathepsin B. Cathepsin B is a lysosomal cysteine protease with a role in intracellular protein degradation. Cathepsin B crosses the blood-brain barrier and elevated levels are implicated in many neurological maladies including traumatic brain injury, epilepsy, and Alzheimer’s disease.
Activity is quantified by release of free fluorescent 4-Methoxy-β-naphthylamine (4MβNA) which excites at 335-350 nm and emits at 410-440 nm
![Angiotensin III, human / Angiotensin II-[Des Asp1], CAS 13602-53-4 - Echelon Biosciences](https://www.echelon-inc.com/wp-content/uploads/2019/11/131-76.jpg)
![Angiotensin I [Asn1,Val5], goosefish - Echelon Biosciences](https://www.echelon-inc.com/wp-content/uploads/2019/11/137-39.jpg)
